GFR alpha 3 Antibody is Antibody is DEAE purified.
免疫原
GFR alpha 3 antibody was raised against a 14 amino acid peptide near the center of murine GFR alpha 3. The immunogen is located within the last 50 amino acids of GFR alpha 3.
GFR alpha 3 antibody can be used for detection of GFR alpha 3 expression by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
GFR alpha 3 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
GFR alpha 3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
GFRA3 antibody, GFRalpha3 antibody, Y15110 antibody, GDNF family receptor alpha 3 antibody, glial cell line derived neurotrophic factor family receptor alpha 3 antibody, Gfra3 antibody, GFRA3 antibody
背景
GFR alpha 3 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRα, and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFRα,-1 and -2, a novel receptor in GFRα, family was identified from human and mouse and designated GFRα,-3. GFRα,-3 binds persephin, thus, persephin, GFRα,-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.