SARS-CoV-2 Spike S2 抗体 (C-Term)
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB, IF, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SARS-CoV-2 Spike S2 抗体
- SARS-CoV-2 Spike S2
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抗原表位
- AA 1130-1180, C-Term
- 适用
- SARS Coronavirus-2 (SARS-CoV-2)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SARS-CoV-2 Spike S2 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 纯化方法
- SARS-CoV-2 (COVID-19) Spike Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-SARS-CoV-2 (COVID-19) Spike S2 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of SARS-CoV-2 (COVID-19) Spike glycoprotein. The immunogen is located within 1130-1180 amino acids of SARS-CoV-2 (COVID-19) Spike protein.
- 亚型
- IgG
- Top Product
- Discover our top product SARS-CoV-2 Spike S2 Primary Antibody
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anti-SARS-CoV-2 Spike S2 antibody
适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: 兔 Monoclonal DM24 unconjugated
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- 应用备注
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WB: 1 μ,g/mL, IHC: 0.1 μ,g/mL, IF: 10 μ,g/mL.
Antibody validated: Immunohistochemistry and Immunofluorescence in human samples. SARS-CoV-2 (COVID-19) Spike antibody can be used for the detection of SARS-CoV-2 (COVID-19) Spike protein in ELISA. It will detect 4 ng of free peptide at 1 μ,g/mL. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- SARS-CoV-2 (COVID-19) Spike Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- SARS-CoV-2 (COVID-19) Spike antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SARS-CoV-2 Spike S2
- Abstract
- SARS-CoV-2 Spike S2 产品
- 别名
- E2 antibody, Surface Glycoprotein antibody, S antibody
- 物质类
- Viral Protein
- 背景
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a Spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Coronavirus invades cells through Spike (S) glycoproteins, a class I fusion protein. It is the major viral surface protein that coronavirus uses to bind to the human cell surface receptor. It also mediates the fusion of host and viral cell membrane, allowing the virus to enter human cells and begin infection (3). The spike protein is the major target for neutralizing antibodies and vaccine development (4). The protein modeling suggests that there is strong interaction between Spike protein receptor-binding domain and its host receptor angiotensin-converting enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of COVID-19 (5). The recent study has shown that the SARS-CoV-2 spike protein binds ACE2 with higher affinity than SARS-CoV spike protein (6).
- 基因ID
- 43740568
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