NCOA2 抗体
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- 抗原 See all NCOA2 抗体
- NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCOA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 550-820 of human NCOA2 (NP_006531.1).
- 亚型
- IgG
- Top Product
- Discover our top product NCOA2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))
- 别名
- NCOA2 (NCOA2 产品)
- 别名
- GRIP1 antibody, KAT13C antibody, NCoA-2 antibody, SRC2 antibody, TIF2 antibody, bHLHe75 antibody, 9530095N19 antibody, D1Ertd433e antibody, GRIP-1 antibody, Grip1 antibody, SRC-2 antibody, TIF-2 antibody, tif2 antibody, wu:fc41a10 antibody, wu:fe26a11 antibody, Tif2 antibody, NCOA2 antibody, XTIF2 antibody, bhlhe75 antibody, grip1 antibody, kat13c antibody, src2 antibody, ncoa2-A antibody, nuclear receptor coactivator 2 antibody, nuclear receptor coactivator 2 S homeolog antibody, NCOA2 antibody, Ncoa2 antibody, ncoa2 antibody, LOC100089041 antibody, ncoa2.S antibody
- 背景
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Synonyms: NCOA2,GRIP1,KAT13C,NCoA-2,SRC2,TIF2,bHLHe75
Background: The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.
- 基因ID
- 10499
- UniProt
- Q15596
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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