LIG4 抗体
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- 抗原 See all LIG4 抗体
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIG4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 612-911 of human LIG4 (NP_002303.2).
- 亚型
- IgG
- Top Product
- Discover our top product LIG4 Primary Antibody
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anti-Ligase IV, DNA, ATP-Dependent (LIG4) (C-Term) antibody
LIG4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 612-911) antibodyLIG4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibodyLIG4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 802-911) antibodyLIG4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 275-324) antibodyLIG4 适用: 人, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibodyKO Validated LIG4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (N-Term) antibodyLIG4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (Center) antibodyLIG4 适用: 人, Cow, 犬 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) antibodyLIG4 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligase IV, DNA, ATP-Dependent (LIG4) (AA 1-911) antibodyLIG4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IF() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
- 别名
- LIG4 (LIG4 产品)
- 别名
- zgc:165595 antibody, lig4 antibody, DNA LIGASE IV antibody, LIG4 antibody, lig4-A antibody, 5830471N16Rik antibody, tiny antibody, DNL4 antibody, ligase IV, DNA, ATP-dependent antibody, DNA ligase 4 antibody, ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining antibody, DNA ligase IV antibody, ligase IV, DNA, ATP-dependent L homeolog antibody, lig4 antibody, LIG4 antibody, LOC100212302 antibody, CpipJ_CPIJ005161 antibody, PTRG_09982 antibody, MCYG_05151 antibody, LOC657210 antibody, ATLIG4 antibody, lig4.L antibody, Lig4 antibody
- 背景
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Synonyms: LIG4,LIG4S
Background: The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.
- 基因ID
- 3981
- UniProt
- P49917
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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