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EGLN1 抗体

EGLN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6989779
发货至: 中国
  • 抗原 See all EGLN1 抗体
    EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
    适用
    • 58
    • 29
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 51
    • 6
    • 2
    克隆类型
    • 54
    • 5
    多克隆
    标记
    • 30
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    • 1
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    • 1
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    This EGLN1 antibody is un-conjugated
    应用范围
    • 51
    • 22
    • 13
    • 13
    • 13
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-426 of human EGLN1 (NP_071334.1).
    亚型
    IgG
    Top Product
    Discover our top product EGLN1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    IF()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    EGLN1 (Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
    别名
    EGLN1 (EGLN1 产品)
    别名
    EGLN1 antibody, egln2 antibody, phd2 antibody, zgc:92314 antibody, AI503754 antibody, C1orf12 antibody, HIF-PH2 antibody, HPH-2 antibody, Hif-p4h-2 antibody, ORF13 antibody, Phd2 antibody, SM-20 antibody, PHD-2 antibody, PHD2 antibody, ECYT3 antibody, HIFPH2 antibody, HPH2 antibody, SM20 antibody, ZMYND6 antibody, egl nine homolog 1 (C. elegans) antibody, egl-9 family hypoxia inducible factor 1 antibody, egl-9 family hypoxia-inducible factor 1 S homeolog antibody, egl-9 family hypoxia-inducible factor 1b antibody, egl-9 family hypoxia-inducible factor 1 antibody, EGLN1 antibody, egln1.S antibody, egln1b antibody, Egln1 antibody
    背景

    Synonyms: EGLN1,C1orf12,ECYT3,HALAH,HIF-PH2,HIFPH2,HPH-2,HPH2,PHD2,SM20,ZMYND6

    Background: The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

    基因ID
    54583
    UniProt
    Q9GZT9
    途径
    cAMP Metabolic Process, Warburg Effect
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