CHRAC1 抗体
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- 抗原 See all CHRAC1 抗体
- CHRAC1 (Chromatin Accessibility Complex 1 (CHRAC1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHRAC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human CHRAC1 (NP_059140.1).
- 亚型
- IgG
- Top Product
- Discover our top product CHRAC1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CHRAC1 (Chromatin Accessibility Complex 1 (CHRAC1))
- 别名
- CHRAC1 (CHRAC1 产品)
- 别名
- chrac1 antibody, CHRAC1 antibody, CHARC1 antibody, CHARC15 antibody, CHRAC-1 antibody, CHRAC-15 antibody, CHRAC15 antibody, YCL1 antibody, 2410152E03Rik antibody, 2810406L04Rik antibody, chromatin accessibility complex 1 antibody, chrac1 antibody, CHRAC1 antibody, Chrac1 antibody
- 背景
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Synonyms: CHRAC1,CHARC1,CHARC15,CHRAC-1,CHRAC-15,CHRAC15,YCL1
Background: DNA replication is initiated by the binding of initiation factors to the origin of replication. Nucleosomes inhibit access to the replication machinery at these origin sequences. Nucleosome remodeling factors increase the accessibility of nucleosomal DNA to transcriptional regulators (1). CHRAC15 and CHRAC17 are subunits of the nucleosomal remodeling factor CHRAC (chromatin accessibility complex),which increases the accessibility of nucleosomal DNA in an ATP-dependent manner (2). Unlike other known chromatin remodelling factors, CHRAC also functions during chromatin assembly by using ATP to convert irregular chromatin into a regular array of nucleosomes with even spacing (3). This conversion process occurs when CHRAC organizes randomly deposited histones into a regularly spaced array (4). In the presence of CHRAC, the nucleosomal ATPase ISWI catalyses several ATP-dependent transitions of chromatin structure (5).
- 基因ID
- 54108
- UniProt
- Q9NRG0
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