HLA-F 抗体
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- 抗原 See all HLA-F (HLAF) 抗体
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This HLA-F antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic Peptide corresponding to C terminal human HLA F.
- 克隆位点
- 4H
- 亚型
- IgG
- Top Product
- Discover our top product HLAF Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
- 别名
- HLA F (HLAF 产品)
- 别名
- HLAF antibody, CDA12 antibody, HLA-5.4 antibody, HLA-CDA12 antibody, major histocompatibility complex, class I, F antibody, HLA-F antibody
- 背景
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Synonyms: CDA12 antibody, HLA 5.4 antibody, HLA class I histocompatibility antigen, alpha chain F antibody, HLA class I molecule antibody, HLA F antigen antibody, HLA-CDA12 antibody, HLA-F antibody, HLAF antibody, HLAF_HUMAN antibody, Leukocyte antigen F antibody, MHC class I antigen F antibody
Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
- 基因ID
- 3134
- UniProt
- P30511
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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