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HLA-F 抗体

HLAF 适用: 人 WB, IHC (p) 宿主: 兔 Monoclonal 4H unconjugated
产品编号 ABIN6989666
发货至: 中国
  • 抗原 See all HLA-F (HLAF) 抗体
    HLA-F (HLAF) (HLA Class I alpha F (HLAF))
    适用
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 14
    • 3
    克隆类型
    • 14
    • 3
    单克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    This HLA-F antibody is un-conjugated
    应用范围
    • 12
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Synthetic Peptide corresponding to C terminal human HLA F.
    克隆位点
    4H
    亚型
    IgG
    Top Product
    Discover our top product HLAF Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    HLA-F (HLAF) (HLA Class I alpha F (HLAF))
    别名
    HLA F (HLAF 产品)
    别名
    HLAF antibody, CDA12 antibody, HLA-5.4 antibody, HLA-CDA12 antibody, major histocompatibility complex, class I, F antibody, HLA-F antibody
    背景

    Synonyms: CDA12 antibody, HLA 5.4 antibody, HLA class I histocompatibility antigen, alpha chain F antibody, HLA class I molecule antibody, HLA F antigen antibody, HLA-CDA12 antibody, HLA-F antibody, HLAF antibody, HLAF_HUMAN antibody, Leukocyte antigen F antibody, MHC class I antigen F antibody

    Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]

    基因ID
    3134
    UniProt
    P30511
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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