HMGN2 抗体
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- 抗原 See all HMGN2 抗体
- HMGN2 (High Mobility Group Nucleosomal Binding Domain 2 (HMGN2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This HMGN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic Peptide within N terminal human HMGN2.
- 克隆位点
- 8H5
- 亚型
- IgG
- Top Product
- Discover our top product HMGN2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- HMGN2 (High Mobility Group Nucleosomal Binding Domain 2 (HMGN2))
- 别名
- HMGN2 (HMGN2 产品)
- 别名
- HMG17 antibody, HMG-17 antibody, Hmg17 antibody, HMGN4 antibody, high mobility group nucleosomal binding domain 2 antibody, high mobility group nucleosomal binding domain 4 antibody, HMGN2 antibody, Hmgn2 antibody, HMGN4 antibody
- 背景
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Synonyms: High mobility group (nonhistone chromosomal) protein 17 antibody, high mobility group nucleosomal binding domain 2 antibody, High mobility group nucleosome-binding domain-containing protein 2 antibody, High mobility group protein N2 antibody, HMG17 antibody, HMGN2 antibody, HMGN2_HUMAN antibody, MGC5629 antibody, Non histone chromosomal protein HMG 17 antibody, Non-histone chromosomal protein HMG-17 antibody, Nonhistone chromosomal protein HMG 17 antibody, nonhistone chromosomal protein hmg-17 antibody
Background: The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription (15). HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates (13,5). HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence (13). Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber (13). In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development (2).
- 基因ID
- 3151
- UniProt
- P05204
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