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ERAP1 抗体

ERAP1 适用: 人 WB 宿主: 兔 Monoclonal 3H62 unconjugated
产品编号 ABIN6989656
发货至: 中国
  • 抗原 See all ERAP1 抗体
    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
    适用
    • 32
    • 17
    • 15
    • 1
    • 1
    宿主
    • 30
    • 2
    克隆类型
    • 29
    • 3
    单克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERAP1 antibody is un-conjugated
    应用范围
    • 18
    • 15
    • 10
    • 10
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Synthetic Peptide corresponding to C-terminal human ERAP1.
    克隆位点
    3H62
    亚型
    IgG
    Top Product
    Discover our top product ERAP1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))
    别名
    ERAP1 (ERAP1 产品)
    别名
    MGC166160 antibody, DKFZp469C044 antibody, ARTS-1 antibody, A-LAP antibody, ALAP antibody, APPILS antibody, ARTS1 antibody, ERAAP antibody, ERAAP1 antibody, PILS-AP antibody, PILSAP antibody, Arts1 antibody, PILSA antibody, Appils antibody, endoplasmic reticulum aminopeptidase 1 antibody, endoplasmic reticulum aminopeptidase 1b antibody, ERAP1 antibody, erap1 antibody, erap1b antibody, Erap1 antibody
    背景

    Synonyms: A LAP antibody, A-LAP antibody, Adipocyte derived leucine aminopeptidase antibody, Adipocyte-derived leucine aminopeptidase antibody, ALAP antibody, Aminopeptidase PILS antibody, Aminopeptidase regulator of TNFR1 shedding antibody, APPILS antibody, ARTS 1 antibody, ARTS-1 antibody, Arts1 antibody, Endoplasmic reticulum aminopeptidase 1 antibody, Endoplasmic reticulum aminopeptidase associated with antigen processing antibody, ERAAP antibody, ERAAP1 antibody, ERAP 1 antibody, Erap1 antibody, ERAP1_HUMAN antibody, KIAA0525 antibody, kiaa0525 protein antibody, PILS AP antibody, PILS-AP antibody, PILSA antibody, PILSAP antibody, Puromycin insensitive leucyl specific aminopeptidase antibody, Puromycin-insensitive leucyl-specific aminopeptidase antibody, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody, type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody, VEGF-induced aminopeptidase antibody

    Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

    基因ID
    51752
    UniProt
    Q9NZ08
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