WAPAL 抗体
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- 抗原 See all WAPAL 抗体
- WAPAL (Wings Apart-Like Protein Homolog (WAPAL))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This WAPAL antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic Peptide within N-terminal human WAPL
- 克隆位点
- 7C15
- 亚型
- IgG
- Top Product
- Discover our top product WAPAL Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- WAPAL (Wings Apart-Like Protein Homolog (WAPAL))
- 别名
- WAPL (WAPAL 产品)
- 别名
- RGD1308960 antibody, FOE antibody, KIAA0261 antibody, WAPL antibody, 2410073G16 antibody, A530089A20Rik antibody, BC037674 antibody, mKIAA0261 antibody, mWAPL antibody, WAPL cohesin release factor antibody, Wapl antibody, WAPL antibody, wapl antibody
- 背景
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Synonyms: FOE antibody, Friend of EBNA2 (Epstein Barr virus nuclear protein 2) antibody, Friend of EBNA2 protein antibody, KIAA0261 antibody, OTTHUMP00000020004 antibody, WAPAL antibody, WAPL antibody, WAPL_HUMAN antibody, Wings apart like homolog antibody, Wings apart like homolog (Drosophila) antibody, Wings apart-like protein homolog antibody
Background: Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Tissue specificity: Isoform 1 is highly expressed in uterine cervix tumor. Isoform 2 is widely expressed with a high level in skeletal muscle and heart.
- 基因ID
- 23063
- UniProt
- Q7Z5K2
- 途径
- Chromatin Binding
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