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EWSR1 抗体

EWSR1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), IF (cc) 宿主: 兔 Monoclonal 4G8 unconjugated
产品编号 ABIN6989630
发货至: 中国
  • 抗原 See all EWSR1 抗体
    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
    适用
    • 70
    • 34
    • 28
    • 11
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 10
    • 2
    • 1
    克隆类型
    • 62
    • 9
    单克隆
    标记
    • 53
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
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    This EWSR1 antibody is un-conjugated
    应用范围
    • 61
    • 27
    • 15
    • 11
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Synthetic Peptide within N terminal human EWSR1/EWS.
    克隆位点
    4G8
    亚型
    IgG
    Top Product
    Discover our top product EWSR1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
    别名
    EWSR1/EWS (EWSR1 产品)
    背景

    Synonyms: bK984G1.4 antibody, bK984G1.4 Ewing sarcoma breakpoint region 1 protein antibody, Ewing sarcoma breakpoint region 1 antibody, Ewing sarcoma breakpoint region 1 protein antibody, Ewings sarcoma EWS Fli1 type 1 oncogene antibody, EWS antibody, EWS oncogene antibody, EWS RNA binding protein 1 antibody, EWS_HUMAN antibody, EWSR 1 antibody, Ewsr1 antibody, EWSR1 protein antibody, RNA binding protein EWS antibody, RNA-binding protein EWS antibody

    Background: EWS is a nuclear RNA-binding protein. As a result of chromosome translocation, the EWS gene is fused to a variety of transcription factors, including ATF-1 in human neoplasias. In the Ewing family of tumors, the N-terminal domain of EWS is fused to the DNA-binding domain of various ETS transcription factors, including Fli-1, Erg, ETV1, E1AF and FEV. The EWS/Fli-1 chimeric protein acts as a more potent transcriptional activator than Fli-1 and can promote cell transformation. Two functional regions have been identified in EWS, an amino-terminal region (domain A), that has little transactivation activity but transforms efficiently when fused to Fli-1, and a distal region (domain B), which shows transactivation activity but transforms less efficiently when fused to Fli-1.

    基因ID
    2130
    UniProt
    Q01844
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