CEND1 抗体
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- 抗原 See all CEND1 抗体
- CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CEND1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Synthetic Peptide within N-terminal Human CEND1.
- 克隆位点
- 1D12
- 亚型
- IgG
- Top Product
- Discover our top product CEND1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
- 别名
- CEND1 (CEND1 产品)
- 别名
- BM88 antibody, 1500001H12Rik antibody, AI415214 antibody, C38 antibody, RGD1309401 antibody, cell cycle exit and neuronal differentiation 1 antibody, CEND1 antibody, Cend1 antibody
- 背景
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Synonyms: BM88 antibody, BM88 antigen antibody, Cell cycle exit and neuronal differentiation 1 antibody, Cell cycle exit and neuronal differentiation protein 1 antibody, FLJ90066 antibody, MGC34326 antibody
Background: BM88 is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.
- 基因ID
- 51286
- UniProt
- Q8N111
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