PLK4 抗体
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- 抗原 See all PLK4 抗体
- PLK4 (Polo-Like Kinase 4 (PLK4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLK4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PLK4/STK18
- 亚型
- IgG
- Top Product
- Discover our top product PLK4 Primary Antibody
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anti-Polo-Like Kinase 4 (PLK4) (N-Term) antibody
Verified PLK4 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Polo-Like Kinase 4 (PLK4) (AA 1-110) antibodyPLK4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1C8 unconjugated
anti-Polo-Like Kinase 4 (PLK4) (AA 724-758) antibodyPLK4 适用: 人 WB 宿主: 兔 Polyclonal RB53118 unconjugated
anti-Polo-Like Kinase 4 (PLK4) antibodyPLK4 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 4 (PLK4) (AA 1-970) antibodyPLK4 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Polo-Like Kinase 4 (PLK4) (AA 1-970) antibodyPLK4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polo-Like Kinase 4 (PLK4) (AA 641-970) antibodyPLK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PLK4 (Polo-Like Kinase 4 (PLK4))
- 别名
- PLK4/STK18 (PLK4 产品)
- 别名
- CG7186 antibody, DmSAK antibody, Dmel\\CG7186 antibody, PLK4 antibody, Plk4 antibody, SAK/PLK antibody, SAK/PLK4 antibody, Sak antibody, plk4 antibody, sak antibody, SAK antibody, STK18 antibody, 1700028H20 antibody, AI385771 antibody, Stk18 antibody, PLK-4 antibody, stk18 antibody, wu:fi33g07 antibody, Sak kinase antibody, polo like kinase 4 antibody, polo-like kinase 4 antibody, polo-like kinase 4 (Drosophila) antibody, serine/threonine-protein kinase PLK4 antibody, SAK antibody, PLK4 antibody, Plk4 antibody, plk4 antibody, LOC5571876 antibody
- 物质类
- Phage Protein
- 背景
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Synonyms: PLK 4, PLK-4, PLK4_HUMAN, Polo like Kinase 4, Polo-like kinase 4, Protein serine/threonine kinase, SAK, Serine/Threonine Kinase 18, Serine/threonine kinase, Serine/threonine protein kinase 18, Serine/threonine protein kinase PLK4, Serine/threonine protein kinase Sak, Serine/threonine-protein kinase 18, Serine/threonine-protein kinase PLK4, Serine/threonine-protein kinase SAK, Snk Akin Kinase, STK 18.
Background: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a posible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2/CHK2.
- 基因ID
- 10733
- UniProt
- O00444
- 途径
- M Phase
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