TTC3 抗体 (AA 251-350) (HRP)
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- 抗原 See all TTC3 抗体
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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抗原表位
- AA 251-350
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTC3 antibody is conjugated to HRP
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF105
- 亚型
- IgG
- Top Product
- Discover our top product TTC3 Primary Antibody
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- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- 别名
- RNF105 (TTC3 产品)
- 别名
- DCRR1 antibody, RNF105 antibody, TPRDIII antibody, 2610202A04Rik antibody, AA409221 antibody, D16Ium21 antibody, D16Ium21e antibody, TPRD antibody, mKIAA4119 antibody, TTC3 antibody, tetratricopeptide repeat domain 3 antibody, E3 ubiquitin-protein ligase TTC3 antibody, TTC3 antibody, Ttc3 antibody, LOC100562480 antibody
- 背景
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Synonyms: DCRR1, E3 ubiquitin protein ligase TTC3, E3 ubiquitin-protein ligase TTC3, Protein DCRR1, RING finger protein 105,Tetratricopeptide repeat protein 3 (TPR repeat protein D), Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, TPRD, TPRDI, TPRDII, TPRDIII, TTC3, TTC3_HUMAN.
Background: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
- 基因ID
- 7267
- UniProt
- P53804
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