MCM2 抗体 (pSer53) (Cy5)
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- 抗原 See all MCM2 抗体
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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抗原表位
- pSer53
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCM2 antibody is conjugated to Cy5
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应用范围
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated Synthesised phosphopeptide derived from human MCM2 around the phosphorylation site of Ser53
- 亚型
- IgG
- Top Product
- Discover our top product MCM2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
- 别名
- MCM2 (MCM2 产品)
- 别名
- CG7538 antibody, DmMCM2 antibody, DmMcm2 antibody, DmeMCM2 antibody, Dmel\\CG7538 antibody, MCM2 antibody, MCM2-7 antibody, MCM2_DROME antibody, McM2 antibody, PCR3 antibody, dMCM2 antibody, l(3)rL074 antibody, XMcm2 antibody, bm28 antibody, ccnl1 antibody, cdc19 antibody, cdcl1 antibody, mitotin antibody, cb737 antibody, chunp6905 antibody, BM28 antibody, CCNL1 antibody, CDCL1 antibody, D3S3194 antibody, MITOTIN antibody, MCM7 antibody, AA959861 antibody, AW476101 antibody, Mcmd2 antibody, mKIAA0030 antibody, Minichromosome maintenance 2 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 2 L homeolog antibody, Mcm2 antibody, mcm2 antibody, MCM2 antibody, mcm2.L antibody
- 背景
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Synonyms: MCM4 (phospho S53), MCM2(phospho-Ser53), MCM2(phospho Ser53), MCM2 (phospho S54), p-MCM2(Ser53), p-MCM2(S53), rat MCM4 (phospho S54), BM28, CCNL 1, CCNL1, CDC like 1, CDC like-1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, cyclin like-1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae), MCM2 minichromosome maintenance deficient 2, mitotin, MCM2_HUMAN, MCM2_MOUSE, MGC10606, Minichromosome maintenance complex component 2, Minichromosome maintenance deficient 2 (mitotin), Minichromosome maintenance deficient 2 mitotin, Minichromosome maintenance protein 2, Minichromosome maintenance protein 2 homolog, Mitotin, Nuclear protein BM28, OTTHUMP00000216047, OTTHUMP00000216050.
Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
- 基因ID
- 4171
- UniProt
- P49736
- 途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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