PAK7 抗体 (Biotin)
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- 抗原 See all PAK7 抗体
- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK7 antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PAK5
- 亚型
- IgG
- Top Product
- Discover our top product PAK7 Primary Antibody
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anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157) antibody
PAK7 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1235 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 621-719) antibodyPAK7 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (C-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 128-157), (N-Term) antibodyPAK7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34659 unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 168-198) antibodyPAK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 600-700) antibodyPAK7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) (AA 26-55), (N-Term) antibodyPAK7 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
- 别名
- PAK5 (PAK7 产品)
- 别名
- PAK5 antibody, pak5 antibody, 2900083L08Rik antibody, 6430627N20 antibody, Pak5 antibody, PAK-5 antibody, PAK-7 antibody, p21 (RAC1) activated kinase 5 antibody, p21 (RAC1) activated kinase 5 L homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 7 antibody, p21 (RAC1) activated kinase 7 antibody, PAK5 antibody, pak5.L antibody, Pak7 antibody
- 背景
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Synonyms: Mbt, mushroom bodies tiny, Pak2,p21 activated kinase 7, p21 protein (Cdc42/Rac)-activated kinase 7, p21(CDKN1A) activated kinase 7, p21-activated kinase 5, p21-activated kinase 7, PAK 5, PAK7, PAK 7, PAK-5, PAK-7, PAK5, PAK7, Protein kinase PAK5, Serine/threonine protein kinase PAK 7, MBT, Serine/threonine-protein kinase PAK 7, PAK7_HUMAN, Protein kinase PAK5.
Background: The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008] Function : Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions. Subunit : Interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Interacts with MARK2, leading to inhibit MARK2 independently of kinase activity. Interacts with RHOD and RHOH.
- 基因ID
- 57144
- UniProt
- P24158
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