Caspase 1 (p10) 抗体 (AA 301-380) (Biotin)
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- 抗原 See all Caspase 1 (p10) (CASP-1 (p10)) products
- Caspase 1 (p10) (CASP-1 (p10))
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抗原表位
- AA 301-380
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 1 (p10) antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse Caspase-1 P10
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- Caspase 1 (p10) (CASP-1 (p10))
- 别名
- Caspase-1 P10 (CASP-1 (p10) 产品)
- 背景
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Synonyms: caspase-1 isoform alpha p10 subunit, CASP 1, CASP1, Caspase 1 apoptosis related cysteine peptidase, Caspase 1 apoptosis related cysteine protease, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1B convertase, IL1BC, IL1BCE, Interleukin 1 beta convertase, Interleukin 1 beta convertase precursor, Interleukin 1 beta converting enzyme. CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p10.
Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
- 基因ID
- 834
- UniProt
- P29452
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