Importin 8 抗体 (AA 1-100) (Biotin)
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- 抗原 See all Importin 8 (IPO8) 抗体
- Importin 8 (IPO8)
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抗原表位
- AA 1-100
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Importin 8 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Cow,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Importin 8
- 亚型
- IgG
- Top Product
- Discover our top product IPO8 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- Importin 8 (IPO8)
- 别名
- Importin 8 (IPO8 产品)
- 别名
- IPO8 antibody, si:ch211-116i17.1 antibody, RANBP8 antibody, 6230418K12Rik antibody, Abcc10 antibody, C130009K11Rik antibody, MRP7 antibody, OM-1 antibody, Om1 antibody, Ranbp8 antibody, importin 8 antibody, IPO8 antibody, ipo8 antibody, Ipo8 antibody
- 背景
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Synonyms: FLJ26580, Imp 8, Imp8, Importin-8, Importin8, IPO 8, IPO8, IPO8_HUMAN, Ran binding protein 8, RAN BP8, Ran-binding protein 8, RANBP 8, RANBP8.
Background: Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.
- 基因ID
- 10526
- UniProt
- O15397
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