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LSM6 抗体 (Biotin)

LSM6 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6982679
发货至: 中国
  • 抗原 See all LSM6 抗体
    LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))
    适用
    • 16
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    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    人, 小鼠
    宿主
    • 13
    • 2
    • 1
    克隆类型
    • 13
    • 2
    多克隆
    标记
    • 11
    • 2
    • 2
    • 1
    This LSM6 antibody is conjugated to Biotin
    应用范围
    • 8
    • 7
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human LSM6:31-80/80
    亚型
    IgG
    Top Product
    Discover our top product LSM6 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))
    别名
    LSM6 (LSM6 产品)
    别名
    zgc:92379 antibody, YDR378C antibody, 1500031N17Rik antibody, 2410088K19Rik antibody, AI747288 antibody, RGD1561937 antibody, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog antibody, LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated antibody, lsm6.S antibody, lsm6 antibody, LSM6 antibody, Lsm6 antibody
    背景

    Synonyms: LSM 6, LSM6 homolog U6 small nuclear RNA associated, LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae), Sm protein F, U6 snRNA associated Sm like protein LSm6, YDR378C.

    Background: Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2, MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] Function : Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA. Subunit : Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape. Similarity : Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.

    基因ID
    11157
    UniProt
    P62312
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