TMEM30A 抗体 (AA 251-350) (AbBy Fluor® 750)
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- 抗原 See all TMEM30A 抗体
- TMEM30A (Transmembrane Protein 30A (TMEM30A))
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抗原表位
- AA 251-350
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适用
- 小鼠, 大鼠, 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TMEM30A antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Transmembrane protein 30A
- 亚型
- IgG
- Top Product
- Discover our top product TMEM30A Primary Antibody
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anti-Transmembrane Protein 30A (TMEM30A) (Middle Region) antibody
TMEM30A 适用: 小鼠, 大鼠, 人, 斑马鱼, 犬, 豚鼠, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 30A (TMEM30A) (N-Term) antibodyTMEM30A 适用: 小鼠, 大鼠, 人, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 30A (TMEM30A) (AA 251-350) antibodyTMEM30A 适用: 小鼠, 大鼠, 人 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 30A (TMEM30A) (AA 108-157) antibodyTMEM30A 适用: 小鼠, 大鼠, 人, 斑马鱼, 犬, 豚鼠, 马, 兔, 非洲爪蟾, Bat, 小鸡, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TMEM30A (Transmembrane Protein 30A (TMEM30A))
- 别名
- Transmembrane protein 30A (TMEM30A 产品)
- 背景
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Synonyms: CDC50A, C6orf67, Cell cycle control protein 50A, P4-ATPase flippase complex beta subunit TMEM30A, Transmembrane protein 30A, TMEM30A
Background: Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes. Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine. Also mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations.
- 基因ID
- 55754
- UniProt
- Q9NV96
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