VPS4B 抗体 (AA 301-400) (AbBy Fluor® 750)
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- 抗原 See all VPS4B (vps4b) 抗体
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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抗原表位
- AA 301-400
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适用
- 人, 小鼠, 鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This VPS4B antibody is conjugated to AbBy Fluor® 750
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 鱼, 人, 小鼠
- 预测反应
- Rat,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human VPS4B
- 亚型
- IgG
- Top Product
- Discover our top product vps4b Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- 别名
- VPS4B (vps4b 产品)
- 别名
- zgc:63682 antibody, vps4a antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody, 8030489C12Rik antibody, Skd1 antibody, vacuolar protein sorting 4 homolog B antibody, vacuolar protein sorting 4 homolog B S homeolog antibody, vacuolar protein sorting 4b homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4 homolog B (S. cerevisiae) antibody, vacuolar protein sorting 4B antibody, Vps4b antibody, vps4b.S antibody, vps4b antibody, VPS4B antibody
- 背景
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Synonyms: 8030489C12Rik, Cell migration inducing 1, Cell migration-inducing gene 1 protein, MGC116271, MIG1, Protein SKD1, Skd1, SKD1B, Suppressor of K(+) transport growth defect 1, Suppressor of K+ transport defect 1, Vacuolar protein sorting 4 homolog B (S. cerevisiae), Vacuolar protein sorting 4 homolog B, Vacuolar protein sorting 4b, Vacuolar protein sorting-associated protein 4B, Vacuolar protein sorting-associating protein 4B, VPS4 2, VPS42, Vps4b, VPS4B_HUMAN.
Background: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).
- 基因ID
- 9525
- UniProt
- O75351
- 途径
- Microtubule Dynamics, CXCR4-mediated Signaling Events
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