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RNF111 抗体 (AA 851-950) (AbBy Fluor® 750)

RNF111 适用: 小鼠, 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN6981667
发货至: 中国
  • 抗原 See all RNF111 抗体
    RNF111 (Ring Finger Protein 111 (RNF111))
    抗原表位
    • 14
    • 8
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    AA 851-950
    适用
    • 39
    • 31
    • 21
    小鼠, 大鼠
    宿主
    • 49
    • 4
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF111 antibody is conjugated to AbBy Fluor® 750
    应用范围
    • 25
    • 23
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RNF111
    亚型
    IgG
    Top Product
    Discover our top product RNF111 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    RNF111 (Ring Finger Protein 111 (RNF111))
    别名
    RNF111 (RNF111 产品)
    别名
    ARK antibody, Arkadia antibody, RNF111 antibody, rnf111 antibody, ark antibody, MGC81253 antibody, MGC146379 antibody, ring finger protein 111 antibody, ring finger 111 antibody, RNF111 antibody, Rnf111 antibody, rnf111-b antibody, rnf111 antibody
    背景

    Synonyms: ARK, Arkadia, DKFZp313E0731, DKFZp686H1966, DKFZp761D081, E3 ubiquitin protein ligase Arkadia, FLJ38008, Ring finger protein 111, RNF 111, RN111_HUMAN.

    Background: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

    基因ID
    54778
    UniProt
    Q6ZNA4
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