EDC4 抗体 (AA 1-100) (AbBy Fluor® 594)
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- 抗原 See all EDC4 抗体
- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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抗原表位
- AA 1-100
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EDC4 antibody is conjugated to AbBy Fluor® 594
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Sheep,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EDC4
- 亚型
- IgG
- Top Product
- Discover our top product EDC4 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
- 别名
- EDC4 (EDC4 产品)
- 别名
- VARICOSE antibody, ge-1 antibody, hedls antibody, rcd-8 antibody, GE1 antibody, Ge-1 antibody, HEDL5 antibody, HEDLS antibody, RCD-8 antibody, RCD8 antibody, BC022641 antibody, si:ch211-237c7.1 antibody, wu:fe26b05 antibody, LRRG00115 antibody, Nrn1l antibody, RGD1309136 antibody, enhancer of mRNA decapping 4 antibody, Transducin/WD40 repeat-like superfamily protein antibody, enhancer of mRNA decapping 4 L homeolog antibody, EDC4 antibody, VCS antibody, edc4 antibody, Edc4 antibody, edc4.L antibody
- 背景
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Synonyms: autoantigen, Autoantigen Ge 1, Autoantigen Ge-1, Autoantigen Ge1, Autoantigen RCD 8, Autoantigen RCD-8, Autoantigen RCD8, edc4, EDC4_HUMAN, Enhancer of mRNA decapping 4, Enhancer of mRNA-decapping protein 4, Ge 1, Hedls, Human enhancer of decapping large subunit, RCD 8.
Background: The major eukaryotic mRNA decay pathway occurs through deadenylation, decapping, and 5' to 3' degradation of the mRNA. Decapping is a critical control point in this decay pathway. Edc4 (enhancer of mRNA decapping 4), also known as human enhancer of decapping large subunit (HEDLS), RCD-8 or Ge-1, is a 1,401 amino acid protein belonging to the WD repeat EDC4 family that is involved in mRNA decapping during mRNA degradation. As part of the mRNA degradation process, Edc4 becomes part of a complex that also contains hDcp1a, hDcp2a, RCK and Edc3. Localizing to P-body and cytoplasm, Edc4 contains a nuclear localization sequence (NLS) which enables it to selectively enter the nucleus as well. Edc4 becomes phosphorylated upon DNA damage and exists as two alternatively spliced isoforms that are encoded by a gene that maps to human chromosome 16q22.1.
- 基因ID
- 23644
- UniProt
- Q6P2E9
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