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ERO1L 抗体 (AA 321-420) (AbBy Fluor® 488)

ERO1L 适用: 人 WB, FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN6977263
发货至: 中国
  • 抗原 See all ERO1L 抗体
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-420
    适用
    • 43
    • 4
    • 4
    宿主
    • 37
    • 5
    • 1
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERO1L antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 43
    • 22
    • 19
    • 15
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    预测反应
    Mouse,Rat,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ERO1L
    亚型
    IgG
    Top Product
    Discover our top product ERO1L Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    别名
    ERO1L (ERO1L 产品)
    别名
    ERO1-L antibody, ero1-alpha antibody, ero1lb antibody, ERO1L antibody, ero1l antibody, ERO1-alpha antibody, ERO1A antibody, zgc:63959 antibody, endoplasmic reticulum oxidoreductase alpha L homeolog antibody, endoplasmic reticulum oxidoreductase 1 alpha antibody, endoplasmic reticulum oxidoreductase alpha antibody, ERO1-like (S. cerevisiae) antibody, ero1a.L antibody, ERO1A antibody, ero1a antibody, Ero1l antibody, Ero1a antibody
    背景

    Synonyms: ERO1-like protein alpha, ERO1A, ERO1-L, ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha, ERO1L

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

    基因ID
    30001
    UniProt
    Q96HE7
    途径
    Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
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