LNX1 抗体 (AA 101-200) (AbBy Fluor® 350)
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- 抗原 See all LNX1 抗体
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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抗原表位
- AA 101-200
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LNX1 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human LNX1
- 亚型
- IgG
- Top Product
- Discover our top product LNX1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
- 别名
- LNX1 (LNX1 产品)
- 别名
- LNX1 antibody, fj78f06 antibody, lnx antibody, si:dkey-12h2.1 antibody, wu:fj78f06 antibody, zgc:152906 antibody, Lnx antibody, LNX antibody, MPDZ antibody, PDZRN2 antibody, ligand of numb-protein X 1 antibody, LNX1 antibody, lnx1 antibody, Lnx1 antibody
- 背景
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Synonyms: E3 ubiquitin protein ligase LNX, Ligand of Numb protein X 1, Ligand of numb protein X 1 E3 ubiquitin protein ligase, LNX, LNX1, LNX1_HUMAN, MPDZ, Multi PDZ domain containing protein E3 ubiquitin protein ligase LNX, Numb binding protein 1, PDZ domain-containing ring finger protein 2, PDZRN2.
Background: Lnx1 is a membrane-bound protein that is involved in signal transduction and protein interactions. Lnx1 is an E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Lnx1 mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.
- 基因ID
- 84708
- UniProt
- Q8TBB1
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