Centaurin beta 2 抗体 (AA 101-200) (AbBy Fluor® 350)
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- 抗原 See all Centaurin beta 2 (ACAP2) 抗体
- Centaurin beta 2 (ACAP2) (ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 2 (ACAP2))
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Centaurin beta 2 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Centaurin beta 2
- 亚型
- IgG
- Top Product
- Discover our top product ACAP2 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Centaurin beta 2 (ACAP2) (ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 2 (ACAP2))
- 别名
- Centaurin beta 2 (ACAP2 产品)
- 别名
- CENTB2 antibody, CNT-B2 antibody, 4832442G16 antibody, 9530039J15Rik antibody, Centb2 antibody, mKIAA0041 antibody, centb2 antibody, MGC81056 antibody, ACAP2 antibody, MGC139548 antibody, cenB1A antibody, si:dkey-254a11.3 antibody, ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 antibody, ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 L homeolog antibody, ACAP2 antibody, Acap2 antibody, acap3.L antibody, acap2 antibody
- 背景
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Synonyms: ACAP 2, ACAP2, ACAP2_HUMAN, ANK repeat and PH domain-containing protein 2, Ankyrin repeat, Arf GAP with coiled coil ANK repeat and PH domains 2, ARF GAP with coiled coil, Arf-GAP with coiled-coil, CENT B 2, Centaurin beta2, Centaurin-beta-2, CENTB 2, CENTB2, Cnt b2, Cnt-b2, Cntb2, KIAA0041, Pleckstrin homology domains 2, Similar to yeast ZINC FINGER PROTEIN GCS1.
Background: The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins mainly regulate membrane traffic. ACAP2 is a member of the centaurin GTPase-activating protein (GAP) family, which comprises a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. ACAP1 and ACAP2 are both widely expressed in peripheral, tubular membranes and usually interact with each other in various tissues. GAP activity of both ACAP1 and ACAP2 is dependent upon phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2]. ACAP2 associates with ARF1 and ARF6. Overexpression of ACAP2 blocks the formation of ARF6-dependent protrusions. K1L is a protein required for growth of the Vaccinia Virus that interacts with the ankyrin repeats of ACAP2.
- 基因ID
- 23527
- UniProt
- Q15057
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