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- 抗原 See all TEAD1 抗体
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TEAD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor)) is a transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif. TEAD1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- This antibody was raised against a recombinant protein fragment within human TEAD1.
- 亚型
- IgG
- Top Product
- Discover our top product TEAD1 Primary Antibody
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anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 135-215) antibody
TEAD1 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (C-Term) antibodyTEAD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 兔, 豚鼠, 马, Pig, 小鸡, 猴, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (Internal Region) antibodyTEAD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (C-Term) antibodyTEAD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 135-215) antibodyTEAD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 适用: 人 WB, ChIP, IP 宿主: 兔 Monoclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) antibodyTEAD1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 324-352), (C-Term) antibodyTEAD1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB20896 unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (N-Term) antibodyTEAD1 适用: 人, 小鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1) (AA 195-244) antibodyTEAD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
- 别名
- TEAD1 (TEAD1 产品)
- 别名
- tead1 antibody, zgc:63696 antibody, TEAD1 antibody, xtead1 antibody, 2610024B07Rik antibody, B230114H05Rik antibody, Gtrgeo5 antibody, TEAD-1 antibody, TEF-1 antibody, Tcf13 antibody, mTEF-1 antibody, AA antibody, NTEF-1 antibody, REF1 antibody, TCF-13 antibody, TCF13 antibody, XNTEF-1 antibody, xlNTEF-1 antibody, TEA domain family member 1a antibody, TEA domain transcription factor 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody, TEA domain family member 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog antibody, TEA domain family member 1b antibody, tead1a antibody, TEAD1 antibody, tead1 antibody, Tead1 antibody, tead1.S antibody, tead1b antibody
- 分子量
- 60 kDa
- NCBI登录号
- NP_068780
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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