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TDG 抗体

TDG 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6972851
发货至: 中国
  • 抗原 See all TDG 抗体
    TDG (Thymine-DNA Glycosylase (TDG))
    适用
    • 48
    • 19
    • 12
    • 2
    • 1
    小鼠
    宿主
    • 37
    • 11
    克隆类型
    • 40
    • 9
    多克隆
    标记
    • 42
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TDG antibody is un-conjugated
    应用范围
    • 38
    • 12
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    产品特性
    In the DNA of higher eukaryotes, hydrolytic deamination of 5-methylcytosine to thymine leads to the formation of G/T mismatches. In addition, TET proteins oxidize 5- methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5- formylcytosine (5fC), and 5-carboxylcytosine (5caC). TDG / Thymine-DNA glycosylase functions to correct G/T mispairs to G/C pairs and plays a role in active DNA demethylation by recognizing 5fC and 5caC and converting these to cystosine through the base excision repair (BER) pathway. TDG / Thymine-DNA glycosylase antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.
    纯化方法
    Protein A Chromatography
    免疫原
    This antibody was raised against a full-length recombinant protein corresponding to mouse thymine DNA glycosylase (TDG).
    亚型
    IgG
    Top Product
    Discover our top product TDG Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    TDG (Thymine-DNA Glycosylase (TDG))
    别名
    TDG / Thymine-DNA glycosylase (TDG 产品)
    别名
    5-MCDG antibody, wu:fb44b11 antibody, zgc:110622 antibody, MGC82456 antibody, MGC89441 antibody, E130317C12Rik antibody, JZA-3 antibody, Jza1 antibody, hTDG antibody, thymine DNA glycosylase antibody, thymine DNA glycosylase, tandem duplicate 1 antibody, putative g/t mismatch-specific thymine DNA glycosylase antibody, G/T mismatch-specific thymine DNA glycosylase antibody, thymine DNA glycosylase S homeolog antibody, thymine-DNA glycosylase antibody, TDG antibody, tdg.1 antibody, Smp_149220 antibody, Tsp_05734 antibody, tdg.S antibody, tdg antibody, Tdg antibody
    分子量
    55 kDa
    NCBI登录号
    NP_766140
    途径
    DNA Damage Repair, Chromatin Binding
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