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- 抗原 See all WWTR1 抗体
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WWTR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- The TAZ / WWTR1 (Transcriptional coactivator with PDZ-binding motif, WW domain-containing transcription regulator protein 1) gene encodes a protein that is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition. TAZ / WWTR1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- TAZ / WWTR1 antibody was raised against a peptide corresponding to the C-terminal region of human TAZ / WWTR1.
- 亚型
- IgG
- Top Product
- Discover our top product WWTR1 Primary Antibody
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anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 1-230) antibody
WWTR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (N-Term) antibodyWWTR1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 201-300) antibodyWWTR1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (C-Term) antibodyWWTR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 296-330), (C-Term) antibodyWWTR1 适用: 人 WB 宿主: 兔 Polyclonal RB51589 unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) (AA 296-330), (C-Term) antibodyWWTR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51590 unconjugated
anti-WW Domain Containing Transcription Regulator 1 (WWTR1) antibodyWWTR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
- 别名
- TAZ / WWTR1 (WWTR1 产品)
- 别名
- WWTR1 antibody, TAZ antibody, 2310058J06Rik antibody, 2610021I22Rik antibody, C78399 antibody, Taz antibody, WW domain containing transcription regulator 1 L homeolog antibody, WW domain containing transcription regulator 1 antibody, wwtr1.L antibody, wwtr1 antibody, WWTR1 antibody, Wwtr1 antibody
- 分子量
- 55 kDa
- NCBI登录号
- NP_056287
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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