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SIRT2 抗体 (C-Term)

SIRT2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6972719
发货至: 中国
  • 抗原 See all SIRT2 抗体
    SIRT2 (Sirtuin 2 (SIRT2))
    抗原表位
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 57
    • 41
    • 37
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 55
    • 10
    • 1
    克隆类型
    • 48
    • 18
    多克隆
    标记
    • 42
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SIRT2 antibody is un-conjugated
    应用范围
    • 46
    • 19
    • 12
    • 12
    • 9
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    产品特性
    SIRT2 is a member of the SIR2 / Sirtuin family of NAD-dependant deacetylase enzymes. It has multiple targets for deacetylation, including tubulin, P53, HOXA10, FOXO3A, P300, FOXO1. SIRT2 suppresses adipogenesis by deacetylating FOXO1, promoting the binding of FOXO1 to PPARg and subsequent repression of PPARg mediated transcriptional activation. Similar to SIRT1, SIRT2 also deacetylates H4AcK16 similar to SIRT1, SIRT2 deacetylates histone H4 at lysine 16. SIRT2 is present in the cytoplasm during most of the cell cycle except in the G2/M transition and in mitosis, where it is found in the nucleus and in contact with chromatin and required for exit from mitosis. SIRT2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
    纯化方法
    Affinity Purified
    免疫原
    This SIRT2 antibody was raised against a synthetic peptide derived from the C-terminal region of human SIRT2.
    亚型
    IgG
    Top Product
    Discover our top product SIRT2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    SIRT2 (Sirtuin 2 (SIRT2))
    别名
    SIRT2 (SIRT2 产品)
    别名
    CG5085 antibody, D.mel2 antibody, Dmel\\CG5085 antibody, SIRT2 antibody, dSIRT2 antibody, sir2 antibody, Sirt2 antibody, BmSirt2 antibody, AtSRT2 antibody, SIRTUIN 2 antibody, T2K12.8 antibody, sirtuin 2 antibody, SIR2 antibody, SIR2L antibody, SIR2L2 antibody, 5730427M03Rik antibody, Sir2l antibody, wu:fb57d05 antibody, zgc:55966 antibody, zgc:77003 antibody, Sirtuin 2 antibody, sirtuin 2 antibody, sirtuin 2 S homeolog antibody, NAD-dependent deacetylase sirtuin 2 homolog antibody, sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) antibody, Sirt2 antibody, SIRT2 antibody, sirt2.S antibody, SRT2 antibody, sirt2 antibody
    分子量
    40 & 45 kDa
    NCBI登录号
    NP_036369
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