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- 抗原 See all SETD7 抗体
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SETD7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- SETD7 / SET7 (SET Domain Containing (Lysine Methyltransferase) 7) is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. SETD7 / SET7 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- This antibody was raised against a peptide within human SETD7 / SET7.
- 亚型
- IgG
- Top Product
- Discover our top product SETD7 Primary Antibody
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anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibody
SETD7 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1B3B8 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3D6G11 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal S4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 159-189) antibodySETD7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2763 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-218) antibodySETD7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (Internal Region) antibodySETD7 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
- 别名
- SETD7 / SET7 (SETD7 产品)
- 别名
- KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
- 分子量
- 60 kDa
- NCBI登录号
- NP_085151
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