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Nanog 抗体 (N-Term)

NANOG 适用: 人, 小鼠 WB, IF, ICC, ChIP-seq, ChIP, CUT&RUN 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6972403
发货至: 中国
  • 抗原 See all Nanog (NANOG) 抗体
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    抗原表位
    • 16
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    • 5
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    N-Term
    适用
    • 137
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    • 1
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    人, 小鼠
    宿主
    • 126
    • 16
    • 3
    • 1
    克隆类型
    • 121
    • 25
    多克隆
    标记
    • 75
    • 9
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    • 5
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    This Nanog antibody is un-conjugated
    应用范围
    • 108
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    • 26
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)
    产品特性
    Nanog (Nanog homeobox) is a transcriptional regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity). Nanog antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    纯化方法
    Affinity Purified
    免疫原
    This antibody was raised against a peptide within the N-terminal region of mouse Nanog.
    亚型
    IgG
    Top Product
    Discover our top product NANOG Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    Nanog (NANOG) (Nanog Homeobox (NANOG))
    别名
    Nanog (NANOG 产品)
    别名
    2410002E02Rik antibody, ENK antibody, ecat4 antibody, NANOG antibody, hacp antibody, wu:fd19e04 antibody, wu:fd20a07 antibody, zgc:193933 antibody, Nanog homeobox antibody, nanog homeobox antibody, Nanog antibody, NANOG antibody, nanog antibody
    分子量
    45 kDa
    NCBI登录号
    NP_082292
    途径
    Stem Cell Maintenance
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