H2AFV 抗体 (C-Term)
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- 抗原 See all H2AFV 抗体
- H2AFV (H2A Histone Family, Member V (H2AFV))
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抗原表位
- C-Term
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适用
- Drosophila melanogaster
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This H2AFV antibody is un-conjugated
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应用范围
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 产品特性
- The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H2A.Z (H2AZ, H2AFZ) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle.In Drosophila, the H2A variant corresponding to H2AZ is H2Av. H2Av is an essential protein in Drosophila and has been implicated in both activation and repression of transcription. H2Av is localized to centromeric heterochromatin in Drosophila and flies lacking H2Av have reduced levels of heterochromatin components at the centromeres. However, H2Av nucleosome distribution throughout the rest of the Drosophila genome correlates with genes that have an open and uniform chromatin architecture at promoter regions. Histone H2Av antibody (mAb) (Clone 10E9.D1) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Drosophila samples.
- 纯化方法
- Protein A Chromatography
- 免疫原
- This antibody was raised against a peptide in the C-terminus of the Drosophila melanogaster Histone variant H2Av.
- 克隆位点
- 10E9-D1
- 亚型
- IgG2a
- Top Product
- Discover our top product H2AFV Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- H2AFV (H2A Histone Family, Member V (H2AFV))
- 别名
- Histone H2Av (H2AFV 产品)
- 别名
- H2A.Z-2 antibody, H2afv antibody, H2AV antibody, h2av antibody, C530002L11Rik antibody, H2a.z-2 antibody, H2av antibody, H2A.F/Z antibody, h2afv antibody, h2afz antibody, H2A histone family, member V antibody, H2A histone family member V antibody, H2A histone family member V S homeolog antibody, H2A histone family, member Va antibody, H2afv antibody, LOC100226437 antibody, H2AFV antibody, h2afv.S antibody, h2afva antibody
- 分子量
- 15 kDa
- NCBI登录号
- NP_524519
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