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- 抗原 See all Histone H1.5 (HIST1H1B) 抗体
- Histone H1.5 (HIST1H1B)
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抗原表位
- pSer17
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Histone H1.5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Dot Blot (DB)
- 产品特性
- The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression. Histone H1.5 is an H1 isotype expressed in somatic cells and is heavily phosphorylated during mitosis. Phosphorylation of H1.5 at serine 17 appears in prometaphase and disappears in telophase. The hyperphosphorylated form of H1.5 is mainly chromatin-bound in metaphase when chromatin is maximally condensed. Phosphorylation of H1.5 at serine 17 can be catalyzed by GSK-3. Histone H1.5S17ph antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot and Western blot, it has been shown to react with Human samples, but it is predicted that it will react with a wide range of sample types.
- 纯化方法
- Affinity Purified
- 免疫原
- This Histone H1.5 phospho Ser17 antibody was raised against a peptide containing phospho Ser17 of human histone H1.5.
- 亚型
- IgG
- Top Product
- Discover our top product HIST1H1B Primary Antibody
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anti-Histone H1.5 (HIST1H1B) (pSer17) antibody
HIST1H1B 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (pThr154) antibodyHIST1H1B 适用: 人 ELISA, WB, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (AA 14-25) antibodyHIST1H1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (pSer188) antibodyHIST1H1B 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (acLys16) antibodyHIST1H1B 适用: 人 ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (AA 681-789) antibodyHIST1H1B 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (AA 63-75) antibodyHIST1H1B 适用: 人 ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (pThr10) antibodyHIST1H1B 适用: 人 ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (AA 6-17) antibodyHIST1H1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone H1.5 (HIST1H1B) (acLys48) antibodyHIST1H1B 适用: 人 ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- Histone H1.5 (HIST1H1B)
- 别名
- Histone H1.5 (HIST1H1B 产品)
- 别名
- H1 antibody, H1.5 antibody, H1B antibody, H1F5 antibody, H1s-3 antibody, H1f5 antibody, histone cluster 1, H1b antibody, histone cluster 1 H1 family member b antibody, HIST1H1B antibody, Hist1h1b antibody
- 分子量
- 36 kDa
- NCBI登录号
- NP_005313
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