Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points. Histone H1 is responsible for establishing higher-order chromatin structure. Histone H1.0 is a unique variant considered a replacement linker histone which is expressed and incorporated into chromatin in the absence of DNA replication. Histone H1.0 is more highly expressed in cells that are growth inhibited or terminally differentiated. Histone H1.0 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human and Mouse samples.
纯化方法
Affinity Purified
免疫原
This antibody was raised against a peptide within the N-terminal region of human Histone H1.0.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
缓冲液
Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
抗原
Histone H1 (H1F0)
(H1 Histone Family, Member 0 (H1F0))