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HIRA 抗体 (AA 421-729)

HIRA 适用: 人, 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal WC119-2H11 unconjugated
产品编号 ABIN6971732
发货至: 中国
  • 抗原 See all HIRA 抗体
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    抗原表位
    • 15
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 421-729
    适用
    • 44
    • 33
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 10
    小鼠
    克隆类型
    • 52
    • 10
    单克隆
    标记
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIRA antibody is un-conjugated
    应用范围
    • 45
    • 24
    • 13
    • 13
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    产品特性
    HIRA (DGCR1, TUP1) is a histone chaperone that preferentially places the variant Histone H3.3 in nucleosomes, replacing canonical Histone H3 during the cell cycle. HIRA is required for the periodic repression of histone gene transcription during the cell cycle and when complexed with ASF1a is involved in the formation of the senescence-associated heterochromatin foci. HIRA antibody (mAb) (Clone WC119.2H11) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    纯化方法
    Protein G Chromatography
    免疫原
    This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
    克隆位点
    WC119-2H11
    亚型
    IgG
    Top Product
    Discover our top product HIRA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • 抗原
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    别名
    HIRA (HIRA 产品)
    别名
    HIRA antibody, wu:fb97b07 antibody, wu:fi43b08 antibody, si:ch211-188g24.3 antibody, AA138857 antibody, D16Ertd95e antibody, N28177 antibody, Tuple1 antibody, DGCR1 antibody, TUP1 antibody, TUPLE1 antibody, dgcr1 antibody, hira-A antibody, tup1 antibody, tuple1 antibody, homolog of histone chaperone HIRA antibody, histone cell cycle regulator antibody, histone cell cycle regulator a antibody, protein HIRA antibody, HIR histone cell cycle regulation defective homolog A (S. cerevisiae) antibody, HIRA antibody, histone cell cycle regulator S homeolog antibody, histone chaperone HIRA-like protein antibody, Tuple1/HirA antibody, HIRA antibody, hira antibody, LOC100052845 antibody, LOC100352472 antibody, LOC100407742 antibody, LOC100450459 antibody, LOC100467668 antibody, LOC100581135 antibody, LOC486424 antibody, Hira antibody, LOC732736 antibody, hira.S antibody
    分子量
    120 kDa
    NCBI登录号
    NP_003316
    途径
    Chromatin Binding
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