Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
产品特性
BCL11A (B-cell CLL/lymphoma 11A) is a transcriptional regulator, a myeloid and B-cell proto-oncogene and plays important roles in leukemogenesis and hematopoiesis. BCL11A is involved in regulating hemoglobin gene expression. BCL11A regulates hemoglobin gene switching during fetal development and silencing of g-globin expression in adults. BCL11A interacts with the Mi-2/NuRD chromatin remodeling complexes, as well as the erythroid transcription factors GATA1 and FOG1. Abundant expression of full-length forms of BCL11A is developmentally restricted to adult erythroid cells. BCL11A antibody (mAb) (Clone BCL11A/123) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western blot, it has been shown to react with Human samples.
纯化方法
Protein G Chromatography
免疫原
This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form).
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
缓冲液
Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.