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- 抗原 See all Actin-Like 6B (ACTL6B) 抗体
- Actin-Like 6B (ACTL6B)
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Actin-Like 6B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- ACTL6B (Actin-Like 6B) Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth (By similarity). ACTL6B antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- This antibody was raised against a peptide within the N-terminal region of human ACTL6B.
- 亚型
- IgG
- Top Product
- Discover our top product ACTL6B Primary Antibody
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anti-Actin-Like 6B (ACTL6B) (AA 1-280) antibody
ACTL6B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 1-280) antibodyACTL6B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) antibodyACTL6B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 42-70), (N-Term) antibodyACTL6B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26766 unconjugated
anti-Actin-Like 6B (ACTL6B) antibodyACTL6B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (Internal Region) antibodyACTL6B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 323-372) antibodyACTL6B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 42-70) antibodyACTL6B 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- Actin-Like 6B (ACTL6B)
- 别名
- ACTL6B (ACTL6B 产品)
- 别名
- MGC110167 antibody, zgc:110167 antibody, ACTL6 antibody, BAF53B antibody, Actl6 antibody, ArpNa antibody, Baf53b antibody, actin-like 6B antibody, actin like 6B antibody, actl6b antibody, ACTL6B antibody, Actl6b antibody
- 分子量
- 50 kDa
- NCBI登录号
- NP_057272
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