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IL-12/IL-23 p40 抗体 (Biotin)

适用: 人, Non-Human Primate ELISA, ELISpot 宿主: 小鼠 Monoclonal MT618 Biotin
产品编号 ABIN6963861
发货至: 中国
  • 抗原 See all IL-12/IL-23 p40 products
    IL-12/IL-23 p40
    适用
    人, Non-Human Primate
    宿主
    • 12
    • 2
    小鼠
    克隆类型
    • 14
    单克隆
    标记
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-12/IL-23 p40 antibody is conjugated to Biotin
    应用范围
    • 9
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, ELISpot
    特异性
    Native and recombinant p40 subunit of IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
    交叉反应 (详细)
    The monoclonal antibody cross-reacts with IL-12/-23 (p40) from non-human primates.
    产品特性
    This monoclonal antibody enables specific detection of the p40 subunit of human IL-12 and IL-23 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples
    纯化方法
    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.
    过滤
    0.2 μm filtered
    免疫原
    Recombinant human IL-23
    克隆位点
    MT618
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    ABIN6963861 and ABIN7448304 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs .

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
    有效期
    18 months
  • Masuta, Yamamoto, Natsume-Kitatani, Kanuma, Moriishi, Kobiyama, Mizuguchi, Yasutomi, Ishii: "An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2067-2075, (2019) (PubMed).

    Weinberger, Joos, Reed, Coler, Grubeck-Loebenstein: "The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age." in: Biogerontology, Vol. 17, Issue 1, pp. 177-87, (2016) (PubMed).

    Min, Wang, Yuan, Kuang, Zhao: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." in: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).

    Wang, Wu, Zhou, Liu, Zhou, Zhu, Song, Zhu, Wang, Xia: "IL12p40 regulates functional development of human CD4+ T cells: enlightenment by the elevated expressions of IL12p40 in patients with inflammatory bowel diseases." in: Medicine, Vol. 94, Issue 10, pp. e613, (2015) (PubMed).

    Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

  • 抗原
    IL-12/IL-23 p40
    别名
    IL12/23 (p40) (IL-12/IL-23 p40 产品)
    基因ID
    3592, 3593
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