IL-12/IL-23 p40 抗体 (Biotin)
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- 抗原 See all IL-12/IL-23 p40 products
- IL-12/IL-23 p40
- 适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL-12/IL-23 p40 antibody is conjugated to Biotin
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应用范围
- ELISA, ELISpot
- 特异性
- Native and recombinant p40 subunit of IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
- 交叉反应 (详细)
- The monoclonal antibody cross-reacts with IL-12/-23 (p40) from non-human primates.
- 产品特性
- This monoclonal antibody enables specific detection of the p40 subunit of human IL-12 and IL-23 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples
- 纯化方法
- Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant human IL-23
- 克隆位点
- MT618
- 亚型
- IgG1
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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ABIN6963861 and ABIN7448304 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAbs .
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
- 有效期
- 18 months
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An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2067-2075, (2019) (PubMed).
: "The stimulatory effect of the TLR4-mediated adjuvant glucopyranosyl lipid A is well preserved in old age." in: Biogerontology, Vol. 17, Issue 1, pp. 177-87, (2016) (PubMed).
: "Effects of repeated tuberculin skin testings on immune responses in experimental monkeys." in: Journal of animal science and technology, Vol. 56, pp. 32, (2015) (PubMed).
: "IL12p40 regulates functional development of human CD4+ T cells: enlightenment by the elevated expressions of IL12p40 in patients with inflammatory bowel diseases." in: Medicine, Vol. 94, Issue 10, pp. e613, (2015) (PubMed).
: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).
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An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8+ T Cells in Nonhuman Primates." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 6, pp. 2067-2075, (2019) (PubMed).
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- 抗原
- IL-12/IL-23 p40
- 别名
- IL12/23 (p40) (IL-12/IL-23 p40 产品)
- 基因ID
- 3592, 3593
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