Fc epsilon RI/FCER1A 抗体 (APC)
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- 抗原 See all Fc epsilon RI/FCER1A (FCER1A) 抗体
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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适用
- 小鼠
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宿主
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Armenian Hamster
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克隆类型
- 单克隆
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标记
- This Fc epsilon RI/FCER1A antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
- 克隆位点
- MAR-1
- 亚型
- IgG
- Top Product
- Discover our top product FCER1A Primary Antibody
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- 应用备注
- This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.
- 说明
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0.2 mg/mL
- 限制
- 仅限研究用
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- 缓冲液
- 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- 2-8°C protected from light
- 有效期
- 12 months
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- 抗原
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
- 别名
- FceR1 (FCER1A 产品)
- 别名
- FCER1A antibody, FCE1A antibody, FcERI antibody, Iger01 antibody, RATIGER01 antibody, Fce1a antibody, Fcr-5 antibody, fcepsilonri antibody, Fc fragment of IgE receptor Ia antibody, Fc receptor, IgE, high affinity I, alpha polypeptide antibody, FCER1A antibody, Fcer1a antibody
- 背景
- The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.
- 基因ID
- 2205
- UniProt
- P20489
- 途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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