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FOXP3 抗体 (APC)

FOXP3 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal MF23 APC
产品编号 ABIN7277971
发货至: 中国
  • 抗原 See all FOXP3 抗体
    FOXP3 (Forkhead Box P3 (FOXP3))
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    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This FOXP3 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
    克隆位点
    MF23
    亚型
    IgG2b
    Top Product
    Discover our top product FOXP3 Primary Antibody
  • 应用备注
    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system. It is recommended to use the Transcription Factor Staining Buffer Kit (TNB-0607-KIT) for optimal staining results with this antibody.
    说明

    0.2 mg/mL

    限制
    仅限研究用
  • 缓冲液
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C protected from light
    有效期
    12 months
  • 抗原
    FOXP3 (Forkhead Box P3 (FOXP3))
    别名
    Foxp3 (FOXP3 产品)
    别名
    foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
    背景
    The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.
    基因ID
    20371
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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