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SIRPA 抗体 (AA 31-370)

SIRPA 适用: 人 FACS, ELISA, IP, IF 宿主: 兔 Monoclonal DM8 unconjugated
产品编号 ABIN6961045
发货至: 中国
  • 抗原 See all SIRPA 抗体
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    抗原表位
    • 16
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-370
    适用
    • 69
    • 39
    • 32
    • 9
    • 8
    • 3
    • 3
    • 3
    宿主
    • 57
    • 31
    • 1
    • 1
    克隆类型
    • 57
    • 33
    单克隆
    标记
    • 45
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRPA antibody is un-conjugated
    应用范围
    • 56
    • 43
    • 19
    • 17
    • 12
    • 11
    • 11
    • 9
    • 9
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    免疫原
    Recombinant human SIRPalpha (Glu31-Arg370) (ABIN6961082) produced by using human HEK293 cells
    克隆位点
    DM8
    亚型
    IgG
    Top Product
    Discover our top product SIRPA Primary Antibody
  • 应用备注
    Flow Cyt  1/100, IP 1/30
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    50 % Glycerol, PBS, pH 7.4, 0.1 % BSA, 0.1 % Procline 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    别名
    SIRPalpha (SIRPA 产品)
    别名
    BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
    背景
    The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.
    分子量
    55 kDa
    基因ID
    140885
    UniProt
    P78324
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