Polyclonal antibody raised in rabbit against human EHF (ETS Homologous Factor), using two synthetic peptides containing a sequence from the central part and the C-terminus of the protein, respectively.
EHF (UniProtKB/Swiss-Prot entry Q9NZC4) belongs to the ETS transcription factor family. This transcriptional activator shows epithelial-specific expression and plays a role in regulating epithelial cell differentiation and proliferation. EHF may also act as a transcriptional repressor of a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. EHF is also a putative tumor suppressor gene and may be involved in carcinogenesis.