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UBA2 抗体

UBA2 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Monoclonal 4F12 unconjugated
产品编号 ABIN6945243
发货至: 中国
  • 抗原 See all UBA2 抗体
    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
    适用
    • 44
    • 15
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 4
    • 1
    克隆类型
    • 36
    • 9
    单克隆
    标记
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This UBA2 antibody is un-conjugated
    应用范围
    • 31
    • 17
    • 15
    • 11
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human UBA2 aa 1-150
    克隆位点
    4F12
    亚型
    IgG
    Top Product
    Discover our top product UBA2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
    别名
    UBA2 (UBA2 产品)
    别名
    ATSAE2 antibody, EMB2764 antibody, EMBRYO DEFECTIVE 2764 antibody, F3K23.23 antibody, F3K23_23 antibody, SUMO-ACTIVATING ENZYME 2 antibody, SUMO-activating enzyme 2 antibody, ARX antibody, SAE2 antibody, AA986091 antibody, Arx antibody, Sae2 antibody, UBA1 antibody, Ubl1a2 antibody, Uble1b antibody, sae2 antibody, sae2-B antibody, uba2-a antibody, uba2-b antibody, uble1b-B antibody, sae2b antibody, uble1b antibody, wu:fi17g06 antibody, zgc:66354 antibody, SUMO1 activating enzyme subunit 2 antibody, SUMO-activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 antibody, ubiquitin-like modifier activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 L homeolog antibody, MICPUN_63834 antibody, MICPUCDRAFT_36729 antibody, SAE2 antibody, UBA2 antibody, Uba2 antibody, uba2.L antibody, uba2 antibody
    背景

    Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115.

    Background: UBA2 (aka SAE2) functions to induce posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, which regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

    基因ID
    10054
    UniProt
    Q9UBT2
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