UBA2 抗体
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- 抗原 See all UBA2 抗体
- UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This UBA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human UBA2 aa 1-150
- 克隆位点
- 4F12
- 亚型
- IgG
- Top Product
- Discover our top product UBA2 Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
- 别名
- UBA2 (UBA2 产品)
- 别名
- ATSAE2 antibody, EMB2764 antibody, EMBRYO DEFECTIVE 2764 antibody, F3K23.23 antibody, F3K23_23 antibody, SUMO-ACTIVATING ENZYME 2 antibody, SUMO-activating enzyme 2 antibody, ARX antibody, SAE2 antibody, AA986091 antibody, Arx antibody, Sae2 antibody, UBA1 antibody, Ubl1a2 antibody, Uble1b antibody, sae2 antibody, sae2-B antibody, uba2-a antibody, uba2-b antibody, uble1b-B antibody, sae2b antibody, uble1b antibody, wu:fi17g06 antibody, zgc:66354 antibody, SUMO1 activating enzyme subunit 2 antibody, SUMO-activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 antibody, ubiquitin-like modifier activating enzyme 2 antibody, ubiquitin like modifier activating enzyme 2 L homeolog antibody, MICPUN_63834 antibody, MICPUCDRAFT_36729 antibody, SAE2 antibody, UBA2 antibody, Uba2 antibody, uba2.L antibody, uba2 antibody
- 背景
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Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115.
Background: UBA2 (aka SAE2) functions to induce posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, which regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.
- 基因ID
- 10054
- UniProt
- Q9UBT2
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