Tropomyosin 抗体
-
- 抗原 See all Tropomyosin (TPM1) 抗体
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This Tropomyosin antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human Tropomyosin 1 aa 100-300.
- 克隆位点
- 2G2
- 亚型
- IgG
- Top Product
- Discover our top product TPM1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
- 别名
- Tropomyosin 1 (TPM1 产品)
- 背景
-
Synonyms: Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, TPM1, C15orf13, TMSA
Background: Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind Actin filaments and function to modulate Actin-Myosin interaction and stabilize Actin filament structure. Tropomyosin _ is encoded by the TPM1 gene, which maps to human chromosome 15q22.1 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with Actin filaments may increase the rigidity of Actin filaments. Tropomyosin also interacts with Caldesmon to regulate smooth muscle contraction.
- 基因ID
- 7168
- UniProt
- P09493
- 途径
- Regulation of Actin Filament Polymerization
-