SUN2 抗体
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- 抗原 See all SUN2 抗体
- SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SUN2 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human SUN2 aa 500-700.
- 克隆位点
- 3G4
- 亚型
- IgG
- Top Product
- Discover our top product SUN2 Primary Antibody
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anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibody
SUN2 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibodySUN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 45-155) antibodySUN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (Internal Region) antibodySUN2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 75-124) antibodySUN2 适用: 人, 大鼠, 小鼠, Cow, 犬, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 326-375) antibodySUN2 适用: 人, 大鼠, 小鼠, 兔, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) (AA 254-303) antibodySUN2 适用: 人, 大鼠, 兔, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibodySUN2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sad1 and UNC84 Domain Containing 2 (SUN2) antibodySUN2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))
- 别名
- SUN2 (SUN2 产品)
- 别名
- UNC84B antibody, B230369L08Rik antibody, C030011B15 antibody, Unc84b antibody, RGD1563141 antibody, Sad1 and UNC84 domain containing 2 antibody, SUN2 antibody, Sun2 antibody
- 背景
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Synonyms: SUN domain-containing protein 2, Protein unc-84 homolog B, Rab5-interacting protein, Sad1/unc-84 protein-like 2, Rab5IP, SUN2, FRIGG, KIAA0668, RAB5IP, UNC84B
Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for interkinetic nuclear migration (INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Required for nuclear migration in retinal photoreceptor progenitors implicating association with cytoplasmic dynein-dynactin and kinesin motor complexes, and probably B-type lamins, SUN1 and SUN2 seem to act redundantly. The SUN1/2:KASH5 LINC complex couples telomeres to microtubules during meiosis, SUN1 and SUN2 seem to act at least partial redundantly. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. May also function on endocytic vesicles as a receptor for RAB5-GDP and participate in the activation of RAB5.
- 基因ID
- 25777
- UniProt
- Q9UH99
- 途径
- Maintenance of Protein Location, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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