SRSF3 抗体
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- 抗原 See all SRSF3 抗体
- SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SRSF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Full length recombinant protein.
- 克隆位点
- 9C11
- 亚型
- IgG
- Top Product
- Discover our top product SRSF3 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
- 别名
- SFRS3 (SRSF3 产品)
- 别名
- SFRS3 antibody, SRp20 antibody, AL024116 antibody, Sfrs3 antibody, X16 antibody, sfrs3 antibody, srp20 antibody, SRP20 antibody, si:zc263a23.9 antibody, zgc:86626 antibody, serine and arginine rich splicing factor 3 antibody, serine/arginine-rich splicing factor 3 antibody, serine/arginine-rich splicing factor 3 S homeolog antibody, serine/arginine-rich splicing factor 3a antibody, SRSF3 antibody, Srsf3 antibody, srsf3.S antibody, srsf3a antibody
- 背景
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Synonyms: Serine/arginine-rich splicing factor 3, SRSF3, Pre-mRNA-splicing factor SRP20, Splicing factor arginine/serine-rich 3, SRP20
Background: Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export. RNA-binding is semi-sequence specific
- 基因ID
- 6428
- UniProt
- P84103
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