RNF40 抗体
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- 抗原 See all RNF40 抗体
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This RNF40 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human RNF40 aa 200-400.
- 克隆位点
- 8D8
- 亚型
- IgG
- Top Product
- Discover our top product RNF40 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IP(1-2 μg) - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
- 别名
- RNF40 (RNF40 产品)
- 别名
- AI848422 antibody, mKIAA0661 antibody, BRE1B antibody, RBP95 antibody, STARING antibody, ring finger protein 40 antibody, RNF40 antibody, Rnf40 antibody
- 背景
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Synonyms: E3 ubiquitin-protein ligase BRE1B, BRE1-B, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RING-type E3 ubiquitin transferase BRE1B, KIAA0661
Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
- 基因ID
- 9810
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