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RNF40 抗体

RNF40 适用: 人, 小鼠, 大鼠 WB, IP, IHC (p) 宿主: 兔 Monoclonal 8D8 unconjugated
产品编号 ABIN6944788
发货至: 中国
  • 抗原 See all RNF40 抗体
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    适用
    • 51
    • 15
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 2
    克隆类型
    • 50
    • 1
    单克隆
    标记
    • 24
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RNF40 antibody is un-conjugated
    应用范围
    • 31
    • 23
    • 10
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human RNF40 aa 200-400.
    克隆位点
    8D8
    亚型
    IgG
    Top Product
    Discover our top product RNF40 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IP(1-2 μg)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    别名
    RNF40 (RNF40 产品)
    别名
    AI848422 antibody, mKIAA0661 antibody, BRE1B antibody, RBP95 antibody, STARING antibody, ring finger protein 40 antibody, RNF40 antibody, Rnf40 antibody
    背景

    Synonyms: E3 ubiquitin-protein ligase BRE1B, BRE1-B, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RING-type E3 ubiquitin transferase BRE1B, KIAA0661

    Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

    基因ID
    9810
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