Reelin 抗体
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- 抗原 See all Reelin (RELN) 抗体
- Reelin (RELN)
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This Reelin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human Reelin aa 241-340
- 克隆位点
- 4C3
- 亚型
- IgG
- Top Product
- Discover our top product RELN Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Reelin (RELN)
- 别名
- Reelin (RELN 产品)
- 别名
- LIS2 antibody, PRO1598 antibody, RL antibody, reeler antibody, rl antibody, Reelen antibody, Rl antibody, reln antibody, RELN antibody, MGC172539 antibody, reelin antibody, reelin L homeolog antibody, RELN antibody, Reln antibody, reln antibody, reln.L antibody, LOC579060 antibody
- 背景
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Synonyms: Reelin, RELN
Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
- 基因ID
- 5649
- UniProt
- P78509
- 途径
- Synaptic Membrane
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