RAS 抗体
-
- 抗原 See all RAS products
- RAS
-
适用
- 人, 大鼠, 小鼠, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This RAS antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human Ras aa 1-100
- 克隆位点
- 11F2
- 亚型
- IgG
-
anti-RAS (AA 31-43) antibody (HRP)
适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-RAS (AA 31-43) antibody适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS (AA 31-43) antibody (FITC)适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-RAS (AA 31-43) antibody (Alkaline Phosphatase (AP))适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-RAS (AA 31-43) antibody (APC)适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-RAS (AA 31-43) antibody (Atto 488)适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-RAS (AA 31-43) antibody (Atto 594)适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-RAS (AA 31-43) antibody (Atto 390)适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-RAS antibody适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAS antibody适用: 人, 大鼠, 小鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- RAS
- Abstract
- RAS 产品
- 别名
- asr antibody, resistance to audiogenic seizures antibody, ras antibody
- 背景
-
Synonyms: GTPase Nras, GTPase Hras, GTPase Kras, NRAS, HRAS, KRAS
Background: Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30 % of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras.
- UniProt
- P01111, P01112, P01116
-
